Edward W. Tupper shows up with Pryor names in a couple of places and even pops up on a historical occasion. I’m passing his name along as it may help you connect the dots with your Pryor research or rule out a connection. Tupper was the son of a Revolutionary War soldier, Benjamin Tupper, from Sharon, MA who settled in Marietta, OH (see Wikipedia)
1800 Land Grant – 19 May 1800. Grantee(s): Edward W Tupper and Allyn PRIOR in Kanawha County, VA. Description: 18,970 acres. Source: Land Office Grants No. 44, 1799-1800, p. 448 (Reel 110). (Allyn is thought to be a revolutionary war soldier from Connecticut.)
1803 Administration of Estate in Washington County, OH – Isaac PRIOR, administrator of Timothy PRIOR. Security: Adam McCurdy, Jacob Ayers. Witnesses: Edward W. Tupper, Matthew Backer, Adam McCordie, Lewis Cass. Dated 23 December 1803. (Timothy Prior is possibly the same man who was on the 1790 Census in Washington Co., PA.)
“Late in the winter of 1806 Floyd bore a letter from (Aaron) Burr to Edward W. Tupper of Marietta (in OH), who had offered his services in case of a war with Spain, and a gift of books on military tactics accompanied the missive.40 From these activities, as emphasized in subsequent disclosures, we may infer that Floyd knew in substance Burr’s plans to invade Mexico.” – The Burr Conspiracy In Indiana, By Isaac J. Cox, pub. 1929.
“General Edward W. Tupper‘s Brigade, Ohio Troops, Sept. 4, 1812 to Jan. 27, 1813.” From “Soldiers of the Revolution and the War of 1812 buried in McLean County, Illinois”